DESCRIPTION JWH-018 POWDER
Buy JWH-018 powder is a synthetic cannabinoid agonist without the .
classical cannabinoid chemical structure.
It was used in scientific research as a tool to study the cannabinoid system.
Buy JWH-018 powder has been identified in herbal incense mixtures, with names including “Spice”, “K2”, and others, sold via the
Internet, gas stations, convenience stores, tobacco shops and head shops.
Licit Uses
JWH-018 was developed and evaluated in basic scientific research to study structure activity relationships related to the cannabinoid receptors.
Pharmacology
Behavioral pharmacology studies show that JWH-018has Δ9-THC-like activity in animals. In mice, it decreases
overall activity, produces analgesia, decreases body
temperature and produces catalepsy.
Together, these foureffects are used by scientists to predict Δ9-THC-like
psychoactivity in humans.
JWH-018’s activity in all four testssuggests that it is likely to have THC-like psychoactive
effects in humans.
In drug discrimination studies in rats, JWH-018generalized to Δ9-THC, i.e. produced subjective effects
similar to those of Δ9-THC.
In vitro studies show that JWH-018 binds to the brain
cannabinoid receptor CB1 with increased affinity relative toΔ9-THC and displays agonist properties in functional
assays, suggesting that it would have the same effects asΔ9-THC in vivo
Illicit Uses
JWH-018 substance has no known legitimate use outside of
research and is purposely spiked on plant material.
It has been identified in numerous herbal incense products including“Spice”, “K2”, and other similar products which are smoked for their psychoactive effects.
User Population
The primary abusers are youth purchasing these substances from Internet websites, gas stations, convenience stores, tobacco shops and head shops.
Control Status
JWH-018 (including its salts, isomers, and salts of isomers) is controlled in schedule I of the Controlled Substances Act.
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