General information Methylone

Buy Methylone online  (methylone) is a designer drug of the phenethylamine class.

Methylone is a
synthetic cathinone with substantial chemical, structural, and
pharmacological similarities to 3,4-methylenedioxymethamphetamine (MDMA, ecstasy).

Animal studies indicate that methylone has MDMA-like and (+) – amphetamine-like behavioral effects. When combined with mephedrone, a controlled schedule I substance, the combination is called “Bubbles.” Other names are given in the above title

Pharmacology

There are substantial pharmacological similarities between methylone and MDMA. Methylone and MDMA, similar to cocaine and methamphetamine, inhibit in vitro the neuronal reuptake of the monoamines dopamine andserotonin and increase concentrations of these monoaminesin the synaptic cleft.

Similar to methamphetamine, methyloneand MDMA also increase, in vitro, the neuronal release of these monoamines.

An increase in monoamineconcentrations in the central nervous system is thought to beinvolved in the pharmacological effects of these substances.
Methylone also resembles MDMA in drug discriminationas says.

Methylone fully substitutes (>80%) for MDMA in ratstrained to discriminate MDMA from saline. Methylone (ED50=6.9 μmol/kg) was about half as potent as MDMA (ED50=3.5 μmol/kg) in these studies. In rats trained to discriminate (+)-amphetamine from saline, both methylone (ED50=10.1 μmol/kg) and MDMA (ED50=7.5 μmol/kg) completely (>80%) substituted for amphetamine with similar potencies. Furthermore, methylone, similar to MDMA, does not substitute for 4-methyl-2,5-dimethoxyamphetamine
(DOM), a schedule I hallucinogen, in rats trained to discriminate DOM from saline.
Because of the structural and pharmacological similarities between methylone and MDMA, the psychoactive effects, adverse health risks, and signs of intoxication resulting from methylone abuse are likely to be similar to those of MDMA. Several chat rooms discussed pleasant and positive effects of methylone when used for recreational purpose

Illicit Distribution:

Law enforcement has encountered methylone in the United States as well as in several countries including the Netherlands, United Kingdom, Japan, and Sweden.

The National Forensic Laboratory Information System (NFLIS) is a DEA database that collects scientifically verified data on drug items and cases submitted to and analyzed by federal, state and local forensic
laboratories in the United States.

The System to Retrieve Information from Drug Evidence (STRIDE)/STARLiMS provides information on drug seizures reported to and analyzed by DEA laboratories. Methylone was first identified by forensic
aboratories in 2009, with five drug reports.

In 2011, there were 1,770 methylone reports with seizure reporting more than
doubling to 4,312 in 2012 and 10,944 in 2013.

Although since permanent scheduling became effective in 2013, laboratories
have identified 4,230 methylone reports in 2014 with a sharp decrease to 369, 186, and 74 reports in 2015, 2016, and 2017,
respectively. For 2018, there were an estimated 38 drug reports.

Methylone has been found in products falsely marketed as research chemicals, plant food, or bath salts.

These products are  often sold at smoke shops, head shops, convenience stores, adult
book stores, and gas stations and can also be purchased on the Internet.

Methylone has been identified in law enforcement seizures that.